What Does A High RDW Mean?

What does Rdw mean in a blood test?

A red cell distribution width (RDW) test is a measurement of the range in the volume and size of your red blood cells (erythrocytes).

Red blood cells move oxygen from your lungs to every cell in your body.

Your cells need oxygen to grow, reproduce, and stay healthy..

Why would lymphocytes be high?

High lymphocyte blood levels indicate your body is dealing with an infection or other inflammatory condition. Most often, a temporarily high lymphocyte count is a normal effect of your body’s immune system working. Sometimes, lymphocyte levels are elevated because of a serious condition, like leukemia.

What is Macrocytic anemia?

Macrocytic anemia, then, is a condition in which your body has overly large red blood cells and not enough normal red blood cells. Different types of macrocytic anemia can be classified depending on what’s causing it. Most often, macrocytic anemias are caused by a lack of vitamin B-12 and folate.

What does high RDW and normal MCV mean?

• A high RDW indicates a large variation in size of RBCs. If the MCV is normal and the RDW is high, there is a mixture of large and small RBCs. If the RDW is normal and the MCV is high, the RBCs are likely all macrocytic. If the MCV and RDW are both normal, the RBCs are likely all about the same normal size.

Why is Rdw high in iron deficiency anemia?

However, a varied size distribution of red blood cells is a hallmark of iron deficiency anemia, and as such shows an increased RDW in virtually all cases. In the case of both iron and B12 deficiencies, there will normally be a mix of both large cells and small cells, causing the RDW to be elevated.

What is Microcytic anemia?

Microcytic anemia definition Microcytosis is a term used to describe red blood cells that are smaller than normal. Anemia is when you have low numbers of properly functioning red blood cells in your body. In microcytic anemias, your body has fewer red blood cells than normal.

What causes anemia?

Iron deficiency anemia. This most common type of anemia is caused by a shortage of iron in your body. Your bone marrow needs iron to make hemoglobin. Without adequate iron, your body can’t produce enough hemoglobin for red blood cells.

What is MCV MCH MCHC RDW in blood work?

The RBC indices are comprised of four different components known as the mean corpuscular hemoglobin concentration (MCHC), the mean corpuscular volume (MCV), the mean corpuscular hemoglobin (MCH), and the red cell distribution width (RDW).

How do you reduce Rdw?

When MCV is low, RDW would increase more significantly. When iron therapy is given, RDW would elevate first and then gradually reduce at the normal level. To diagnose small cell and low pigment anaemia. To classify anaemia.

What happens if you have high red blood cells?

A high red blood cell count may be a symptom of a disease or disorder, although it doesn’t always indicate a health problem. Health or lifestyle factors can cause a high red blood cell count. Medical conditions that can cause an increase in red blood cells include: Heart failure, causing low blood oxygen levels.

What does a low RDW mean?

A low RDW (below 10.2%) means that the red blood cells vary very little in size. One reason for a low RDW level is macrocytic anemia. Another cause of a low RDW level is microcytic anemia.

What is the normal range for Rdw SD?

The width of the distribution curve is measured at the point that is 20% above the baseline. Since the RDW-SD is an actual measurement, it is not influenced by the MCV and more accurately reflects the red cell size variance. The normal RDW-SD range for adults is 40.0 – 55.0 fL.

What is considered high RDW?

A high RDW (over 14.5%) means that the red blood cells vary a lot in size. A normal RDW is 11.6 to 14.6%, but researchers from the Intermountain Medical Center Heart Institute found that patients with a RDW level greater than or equal to 12.9% had an increased risk for depression.

Is high RDW serious?

If your RDW is too high, it could be an indication of a nutrient deficiency, such as a deficiency of iron, folate, or vitamin B-12. These results could also indicate macrocytic anemia, when your body doesn’t produce enough normal red blood cells, and the cells it does produce are larger than normal.

Is low Rdw bad?

If the results of a CBC show low levels of red blood cells or hemoglobin, this usually suggests anemia. Doctors will then try to determine the cause of the condition using the RDW and other tests.